Volume 1 Issue 2

Designer Drugs: A Synthetic Catastrophe

James Fratantonio, Lawrence Andrade and Marcelo Febo
Synthetic stimulants can cause hallucinations, aggressive behaviors, death and are sometimes legal. These substances are sold as plant food and bath salts that are “Not for Human Consumption”, therefore skirting the 1986 Federal Analogue Act and giving a false pretense of safety.

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Coupling Neurogenetics (GARS™) and a Nutrigenomic Based Dopaminergic Agonist to Treat Reward Deficiency Syndrome (RDS): Targeting Polymorphic Reward Genes for Carbohydrate Addiction Algorithms

Kenneth Blum, Thomas Simpatico, Rajendra D. Badgaiyan, Zsolt Demetrovics, James Fratantonio, et al.
Earlier work from our laboratory, showing anti-addiction activity of a nutraceutical consisting of amino-acid precursors and enkephalinase inhibition properties and our discovery of the first polymorphic gene (Dopamine D2 Receptor Gene [DRD2]) to associate with severe alcoholism serves as a blue-print for the development of “Personalized Medicine” in addiction.

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Epigenetic Changes Induced by Exercise

Trevor Archer
Physical exercise offers an epigenetic propensity that holds benefits with several health domains, particularly for children and adolescents. Yet, it is only recently that that regular exercise has begun to be construed as a positive epigenetic mechanism to modify the genome-wide DNA methylation pattern in humans [1].

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